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1

Gene regulation and DNA damage in the ageing human brain

Lu, Tao, Pan, Ying, Kao, Shyan-Yuan, Li, Cheng, Kohane, Isaac, Chan, Jennifer, Yankner, Bruce A.

Journal:

Year:

2004

Language:

english

File:

PDF, 652 KB

english, 2004

2

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

Nakagawa, Toshiyuki, Zhu, Hong, Morishima, Nobuhiro, Li, En, Xu, Jin, Yankner, Bruce A., Yuan, Junying

Journal:

Year:

2000

Language:

english

File:

PDF, 453 KB

english, 2000

3

Neural mechanisms of ageing and cognitive decline

Bishop, Nicholas A., Lu, Tao, Yankner, Bruce A.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.66 MB

english, 2010

4

Monster plaques: What they tell us about Alzheimer's disease

Yankner, Bruce A.

Journal:

Nature Medicine

Year:

1998

File:

PDF, 328 KB

1998

5

Mechanisms of Neuronal Degeneration in Alzheimer's Disease

Bruce A. Yankner

Journal:

Year:

1996

Language:

english

File:

PDF, 160 KB

english, 1996

6

The Biology and Mechanism of Action of Nerve Growth Factor

Yankner, B A, Shooter, E M

Journal:

Annual Review of Biochemistry

Year:

1982

Language:

english

File:

PDF, 652 KB

english, 1982

7

Sorting Out Presenilins in Alzheimer’s Disease

Wolfe, Michael S., Yankner, Bruce A.

Journal:

Year:

2016

Language:

english

File:

PDF, 567 KB

english, 2016

8

Cerebral granulomatous angiitis associated with isolation of human T-lymphotropic virus type III from the central nervous system

Bruce A. Yankner, Paul R. Skolnik, Gregory M. Shoukimas, Dana H. Gabuzda, Raymond A. Sobel, Dr David D. Ho

Journal:

Annals of Neurology

Year:

1986

Language:

english

File:

PDF, 836 KB

english, 1986

9

Secretogranin I/Chromogranin B Is a Heparin-Binding Adhesive Protein

Ming Chen, Paul Tempst, Bruce A. Yankner

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 1.68 MB

english, 1992

10

Inhibition of β-Amyloid Production by Activation of Protein Kinase C

Dana Gabuzda, Jorge Busciglio, Bruce A. Yankner

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 650 KB

english, 1993

11

The Pathogenesis of Alzheimer's Disease: Is Amyloid β-Protein the Beginning or the End?

BRUCE A. YANKNER

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

12

10.1038/10037

Yuan, Junying, Yankner, Bruce A.

Journal:

Nature Cell Biology

Year:

1999

Language:

english

File:

PDF, 100 KB

english, 1999

13

10.1038/27208

Yankner, Bruce A., Zhang, Zhuohua, Hartmann, Henrike, Minh Do, Viet, Abramowski, Dorothee, Sturchler-Pierrat, Christine, Staufenbiel, Matthias, Sommer, Bernd, van de Wetering, Marc, Clevers, Hans, Saf

Journal:

Year:

1998

Language:

english

File:

PDF, 707 KB

english, 1998

14

10.1038/35004673

Yankner, Bruce A.

Journal:

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

15

10.1038/35017108

Yankner, Bruce A., Zhang, Zhuohua, Nadeau, Philip, Song, Weihong, Donoviel, Dorit, Yuan, Menglan, Bernstein, Alan

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 188 KB

english, 2000

16

10.1038/35037739

Yuan, Junying, Yankner, Bruce A.

Journal:

Year:

2000

Language:

english

File:

PDF, 476 KB

english, 2000

17

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

Lorenzo, Alfredo, Razzaboni, Bronwyn, Weir, Gordon C., Yankner, Bruce A.

Journal:

Year:

1994

File:

PDF, 729 KB

1994

18

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro

Busciglio, Jorge, Yankner, Bruce A.

Journal:

Year:

1995

File:

PDF, 1.11 MB

1995

19

10.1038/74833

Yankner, Bruce A., Lorenzo, Alfredo, Yuan, Menglan, Zhang, Zhuohua, Paganetti, Paolo A., Sturchler-Pierrat, Christine, Staufenbiel, Matthias, Mautino, Jorge, Vigo, Francisco Sol, Sommer, Bernd

Journal:

Nature Neuroscience

Year:

2000

Language:

english

File:

PDF, 249 KB

english, 2000

20

10.1038/87839

Weninger, Stacie C., Yankner, Bruce A.

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 36 KB

english, 2001

21

Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease

Xu, Jin, Kao, Shyan-Yuan, Lee, Frank J.S., Song, Weihong, Jin, Lee-Way, Yankner, Bruce A.

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 444 KB

english, 2002

22

Aging renders the brain vulnerable to amyloid β-protein neurotoxicity

Guela, Changiz, Wu, Chuang-Kuo, Saroff, Daniel, Lorenzo, Alfredo, Yuan, Menglan, Yankner, Bruce A.

Journal:

Nature Medicine

Year:

1998

File:

PDF, 670 KB

1998

23

β-Amyloid Neurotoxicity in Human Cortical Culture Is Not Mediated by Excitotoxins

Jorge Busciglio, John Yeh, Bruce A. Yankner

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 768 KB

english, 1993

24

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

Yankner, B., Duffy, L., Kirschner, D.

Journal:

Year:

1990

Language:

english

File:

PDF, 1.08 MB

english, 1990

25

The Aging Brain

Yankner, Bruce A., Lu, Tao, Loerch, Patrick

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2008

Language:

english

File:

PDF, 694 KB

english, 2008

26

β-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding

Jorge Busciglio, Alfredo Lorenzo, John Yeh, Bruce A Yankner

Journal:

Year:

1995

Language:

english

File:

PDF, 5.96 MB

english, 1995

27

Negative Regulation of Vps34 by Cdk Mediated Phosphorylation

Tsuyoshi Furuya, Minsu Kim, Marta Lipinski, Juying Li, Dohoon Kim, Tao Lu, Yong Shen, Lucia Rameh, Bruce Yankner, Li-Huei Tsai, Junying Yuan

Journal:

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

28

The Aging Stress Response

Marcia C. Haigis, Bruce A. Yankner

Journal:

Year:

2010

Language:

english

File:

PDF, 534 KB

english, 2010

29

The biology and pathology of presenilins

Bruce A. Yankner

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 172 KB

english, 2000

30

Regulation of notch-1 cleavage and signaling by presenilin-1

Weihong Song, Philip M. Nadeau, Menglan Yuan, Xudong Yang, Jie Shen, Bruce A. Yankner

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 147 KB

english, 2000

31

Regulation of endogenous amyloid β-protein production by APOE in a human cortical culture model

Philip M. Nadeau, Menglan Yuan, Changiz Geula, Karl Weisgraber, Steven G. Younkin, Bruce A. Yankner

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

32

P1-280 APP-mediated signal transduction in the absence of presenilins

Matthew R. Hass, Bruce A. Yankner

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

33

803 A primate model of ßamyloid-induced neurotoxicity and tau phoaphorylation

C. Geula, C.-K. Wu, D.M. Saroff, A. Lorenzo, B.A. Yankner

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 138 KB

english, 1996

34

Distinct Processing of Endogenous and Overexpressed Recombinant Presenilin 1

K Baumann, P.A Paganetti, C Sturchler-Pierrat, C Wong, H Hartmann, R Cescato, P Frey, B.A Yankner, B Sommer, M Staufenbiel

Journal:

Neurobiology of Aging

Year:

1997

Language:

english

File:

PDF, 604 KB

english, 1997

35

Altered Metabolism of the Amyloid β Precursor Protein Is Associated with Mitochondrial Dysfunction in Down's Syndrome

Jorge Busciglio, Alejandra Pelsman, Caine Wong, Gustavo Pigino, Menglan Yuan, Hiroshi Mori, Bruce A. Yankner

Journal:

Year:

2002

Language:

english

File:

PDF, 936 KB

english, 2002

36

A RIP Tide in Neuronal Signal Transduction

Julius O Ebinu, Bruce A Yankner

Journal:

Year:

2002

Language:

english

File:

PDF, 115 KB

english, 2002

37

S5-02-03: Expression studies

Bruce A. Yankner

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 50 KB

english, 2006

38

72 Characterization of S182 (presenilin 1) and its effect on ßA4

M. Staufenbiel, K.-H. Baumann, C. Sturchler-Pierrat, K.-H. Wiederhold, A. Probst, P. Paganetti, P. Frey, B. Yankner, B. Sommer

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 138 KB

english, 1996

39

574 Localization and functional significance of presenilin S182

B.A. Yankner, H. Hartmann, C. Wong, J. Busciglio, A. Lorenzo, M. Staufenbiel

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 141 KB

english, 1996

40

Amyloid Fibril Toxicity in Alzheimer's Disease and Diabetes

A. LORENZO, B. A. YANKNER

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

41

Altered Social Behavior and Neuronal Development in Mice Lacking the Uba6-Use1 Ubiquitin Transfer System

Lee, Peter C.W., Dodart, Jean-Cosme, Aron, Liviu, Finley, Lydia W., Bronson, Roderick T., Haigis, Marcia C., Yankner, Bruce A., Harper, J. Wade

Journal:

Year:

2013

Language:

english

File:

PDF, 1.98 MB

english, 2013

42

Physiology: Inflammation links ageing to the brain

Gabuzda, Dana, Yankner, Bruce A.

Journal:

Year:

2013

Language:

english

File:

PDF, 519 KB

english, 2013

43

In vivo neurotoxicity of beta-amyloid [Î²(1â40)] and the Î²(25â35) fragment

Kowall, N.W., McKee, A.C., Yankner, B.A., Beal, M.F.

Journal:

Neurobiology of Aging

Year:

1992

Language:

english

File:

PDF, 1.55 MB

english, 1992

44

The histone demethylase LSD1/KDM1A promotes the DNA damage response

Mosammaparast, N., Kim, H., Laurent, B., Zhao, Y., Lim, H. J., Majid, M. C., Dango, S., Luo, Y., Hempel, K., Sowa, M. E., Gygi, S. P., Steen, H., Harper, J. W., Yankner, B., Shi, Y.

Journal:

The Journal of Cell Biology

Year:

2013

Language:

english

File:

PDF, 4.32 MB

english, 2013

45

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

Yankner, B., Dawes, L., Fisher, S, Villa-Komaroff, L, Oster-Granite, M., Neve, R.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.35 MB

english, 1989

46

REST and stress resistance in ageing and Alzheimer’s disease

Lu, Tao, Aron, Liviu, Zullo, Joseph, Pan, Ying, Kim, Haeyoung, Chen, Yiwen, Yang, Tun-Hsiang, Kim, Hyun-Min, Drake, Derek, Liu, X. Shirley, Bennett, David A., Colaiácovo, Monica P., Yankner, Bruce A.

Journal:

Year:

2014

Language:

english

File:

PDF, 6.11 MB

english, 2014

47

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

Sun, Fang, Park, Kevin K., Belin, Stephane, Wang, Dongqing, Lu, Tao, Chen, Gang, Zhang, Kang, Yeung, Cecil, Feng, Guoping, Yankner, Bruce A., He, Zhigang

Journal:

Year:

2011

Language:

english

File:

PDF, 2.04 MB

english, 2011

48

Methodological variables in the assessment of beta amyloid neurotoxicity

Busciglio, Jorge, Lorenzo, Alfredo, Yankner, Bruce A.

Journal:

Neurobiology of Aging

Year:

1992

Language:

english

File:

PDF, 793 KB

english, 1992

49

Amyloid and Alzheimer's disease—Cause or effect?

Yankner, Bruce A.

Journal:

Neurobiology of Aging

Year:

1989

Language:

english

File:

PDF, 224 KB

english, 1989

50

An antibody to β amyloid and the amyloid precursor protein inhibits cell-substratum adhesion in many mammalian cell types

Chen, Ming, Yankner, Bruce A.

Journal:

Neuroscience Letters

Year:

1991

Language:

english

File:

PDF, 416 KB

english, 1991